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What Causes Seizures
in Dogs & Cats

Understanding the potential causes of seizures in our pets

Dillon Devathasan

By Dr. Dillon Devathasan, DVM MS DACVIM (Neurology)

Board certified veterinary neurologist

May 20, 2025 |  3 min read |  Start here series

On this page

Extracranial Factors 

Intracranial Factors

Idiopathic Epilepsy

Why Veterinary Investigation Is Essential

 
idiopathic seizures in dogs
Key Takeaways
Seizures are a symptom, not a disease itself
Seizures can be caused by problems inside or outside the brain
Idiopathic epilepsy is the most common cause of seizures in dogs
Veterinary investigation is important to identify underlying cause and to guide treatment
Seizures happen when there is abnormal electrical activity in the brain. Many different conditions can trigger this abnormal activity. In pets, seizures are generally classified by their underlying cause into three broad categories: 1) Extracranial causes, 2) Intracranial causes & 3) Idiopathic epilepsy. 

Extracranial Causes

Extracranial causes are conditions outside of the brain that can cause seizures. These causes can be caused by organ-related, metabolic disease or toxins. Examples include:
  • Low blood sugar 
  • Kidney disease
  • Toxin exposure   (e.g. metaldehyde, organophosphates, chocolates, lead)
  • Liver disease
 
  • Endocrine diseases (e.g. hypothyroidism)
  • Electrolyte imbalances (e.g. hypocalcemia)
  • Portosystemic shunt

Intracranial Causes

Intracranial causes are problems within the brain that can lead to seizures. Examples include: 
  • Brain tumors
  • Inflammation of the brain
  • Trauma or head injury
  • Congenital abnormality
 
  • Strokes
  • Infection
  • Degenerative disease
Our Seizure Diary helps you record events, identify patterns and share important information with your vet.

Track & understand seizures

idiopathic epilepsy in dogs
Brain in dog seizure

When To Seek Emergency Care 

Multiple seizures within 24 hours

Seizures lasting more than 5 minutes 

Your pet does not return to normal for an extended period

Your pet is injured during the seizure

This is your pet's first seizure

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Idiopathic Epilepsy

Idiopathic epilepsy is diagnosed when no underlying cause for the seizures can be identified despite thorough veterinary investigation, which may include blood tests, advanced imaging such as MRI, and cerebrospinal fluid (spinal tap) analysis.

It is the most common cause of recurrent seizures in dogs and is believed to have a genetic basis in many breeds.

Idiopathic epilepsy most commonly develops between 6 months and 6 years of age, with severity and seizure frequency varying between individuals.

Many dogs with idiopathic epilepsy are otherwise neurologically normal between seizure episodes and can continue to live happy, fulfilling lives with appropriate long-term management and veterinary care.
Why Veterinary Investigation is Essential
Because seizures can be caused by many different conditions (some treatable and some more serious), it is essential that your veterinarian perform a thorough examination and diagnostic testing. 

Identifying the underlying cause is critical to ensure your pet receives most effective treatment.
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Disclaimer: Pet Seizure Hub provides educational information only and is not a substitute for veterinary examination, diagnosis, or treatment. Always consult your veterinarian or veterinary neurologist regarding your pet’s health.

If your pet is experiencing an emergency, seek immediate veterinary attention.

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